enlarged. No increase of fluid in the pleural, pericardial or peritoneal cavities.

Heart .—A considerable amount of jelly-like material round the base. There are a few petechiæ over right auricle. There are no petechiæ under endocardium. The muscle is pale. The blood of this organ contains trypanosomes.

Lungs .—Both show small extravasations under pleural membrane, otherwise nothing noteworthy.

Liver .—Nothing noteworthy.

Spleen .—Slightly enlarged ; substance is soft and friable. Smears from this organ show the presence of trypanosomes.

Kidneys .—J elly-like substance surrounds both.

Glands .—Along the great vessels they are distinctly enlarged.

Uterus .—Contains two practically full time foetuses. The heart blood of the foetus shows no trypanosomes, nucleated red corpuscles were abundant.

Remaries . —This experiment is an interesting and important one. Its object was to determine firstly the effect of injection of blood containing the “ mule variety of trypanosome,” and secondly, when this latter failed to appear in the blood, to determine whether the “ Jinja cattle ” trypanosome would develop in the blood of the same animal. The first injection was not followed by the appearance of trypanosomes in the blood, although two inoculations were performed, but when the blood containing the “ Jinja variety ” of trypanosome was injected the parasites appeared in the blood after the usual incubation period for this disease and continued to be present until the death. The death was due to the trypanosomes, perhaps hastened by the pregnancy. The above experiment suggests that as regards their action in goats there is a difference between the trypanosomes of the “mule” and the “ .Jinja cattle.”

16. Are tee dealing with one or more than one species of Trypanosoma 1

As has been shown the Trypanosoma gambiense differs in morphological characters from the animal varieties studied here. The difference is more marked in their behaviour when inoculated into the various experimental animals. From a consideration of the results obtained, the first conclusion that will be arrived at is that the trypanosomes found in the animals in Uganda are different from those found in sleeping sickness cases, and in men showing no signs of sleeping sickness, the two latter trypanosomes being identical, being in fact the Trypanosoma gambiense of the West Coast. As to the nature of the animal trypanosomes, the facts may be summed up as follows:—The trypanosoma of Mr. Pordage’s ox when inoculated into a monkey and dog failed to appear in the blood of either; it further appeared and developed in the blood of an ox. In these results a difference is established (7390) 0